Immune System and Social Security Disability
Autoimmune and immune-deficiency disorders that can affect joints, organs, stamina, or infection risk.
Immune-system disorders can affect joints, skin, kidneys, lungs, the nervous system, or infection risk. Adult Listing 14.00 includes systemic lupus erythematosus, inflammatory arthritis, and other immune impairments. Listings often require involvement of particular organs or combinations of findings — not only a positive antibody test.
Fatigue, flares, and medication side effects frequently drive residual functional capacity when a listing is not met.
Browse the immune-system guides below, or return to the Disability Conditions Center.
Official SSA resource: Listing 14.00 — Immune System Disorders
Immune System condition guides
- Lupus
Systemic lupus can affect joints, skin, kidneys, lungs, blood, or the nervous system. Listing 14.02 requires defined organ involvement or repeated manifestations with serious functional limits.
- Inflammatory Arthritis
A broad group of immune-mediated joint and spine diseases, including psoriatic arthritis and ankylosing spondylitis. Listing 14.09 has several disease-pattern pathways.
- Rheumatoid Arthritis
An inflammatory autoimmune arthritis. SSA may evaluate it under Listing 14.09 when the current immune-system criteria are met.
- Crohn’s Disease
Crohn’s disease is an inflammatory bowel disease. Listing 5.06 uses documented intestinal disease plus specified obstruction, laboratory, nutritional, perianal, or repeated-complication criteria.
- Fibromyalgia
A medically determinable impairment under SSR 12-2p when diagnostic criteria are documented. There is no fibromyalgia listing.
- Osteoarthritis
Joint cartilage wear that can limit standing, walking, or use of the hands. SSA may consider Listing 1.18 when a major joint meets current criteria.
Speak with a Social Security Disability attorney
Brock & Stout can review a Social Security Disability claim, look for missing medical evidence, and discuss next steps. We do not charge a fee for SSD representation unless we win.
This page is general educational information about Social Security Disability as of the date of this publication. It is not legal or medical advice, does not create an attorney-client relationship, and does not guarantee results. Eligibility depends on individual facts and current Social Security rules.
